2vdo
From Proteopedia
Contents |
INTEGRIN ALPHAIIBBETA3 HEADPIECE BOUND TO FIBRINOGEN GAMMA CHAIN PEPTIDE, HHLGGAKQAGDV
Template:ABSTRACT PUBMED 18710925
About this Structure
2vdo is a 5 chain structure of Fibrinogen with sequence from Homo sapiens and Mus musculus. The February 2011 RCSB PDB Molecule of the Month feature on Integrin by David Goodsell is 10.2210/rcsb_pdb/mom_2011_2. Full crystallographic information is available from OCA.
See Also
Reference
- Springer TA, Zhu J, Xiao T. Structural basis for distinctive recognition of fibrinogen gammaC peptide by the platelet integrin alphaIIbbeta3. J Cell Biol. 2008 Aug 25;182(4):791-800. Epub 2008 Aug 18. PMID:18710925 doi:jcb.200801146
- Xiao T, Takagi J, Coller BS, Wang JH, Springer TA. Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics. Nature. 2004 Nov 4;432(7013):59-67. Epub 2004 Sep 19. PMID:15378069 doi:http://dx.doi.org/10.1038/nature02976
Categories: Homo sapiens | Integrin | Mus musculus | RCSB PDB Molecule of the Month | Springer, T A. | Xiao, T. | Zhu, J. | Antagonist | Cell adhesion | Cell adhesion-immune system complex | Cleavage on pair of basic residue | Disease mutation | Fibrinogen binding | Glycoprotein | Host-virus interaction | Membrane | Phosphorylation | Platelet integrin alphaiibbeta3 | Pyrrolidone carboxylic acid | Receptor | Transmembrane
