3awv

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Template:STRUCTURE 3awv

Crystal structure of Streptomyces tyrosinase in a complex with caddie soaked in a Cu(II)-containing solution for 80 hr: occupancy of CuA is low

Template:ABSTRACT PUBMED 21730070

About this Structure

3awv is a 2 chain structure with sequence from Streptomyces castaneoglobisporus. Full crystallographic information is available from OCA.

Reference

  • Matoba Y, Bando N, Oda K, Noda M, Higashikawa F, Kumagai T, Sugiyama M. A molecular mechanism for copper transportation to tyrosinase that is assisted by a metallochaperone, caddie protein. J Biol Chem. 2011 Aug 26;286(34):30219-31. Epub 2011 Jul 5. PMID:21730070 doi:10.1074/jbc.M111.256818
  • Matoba Y, Kumagai T, Yamamoto A, Yoshitsu H, Sugiyama M. Crystallographic evidence that the dinuclear copper center of tyrosinase is flexible during catalysis. J Biol Chem. 2006 Mar 31;281(13):8981-90. Epub 2006 Jan 25. PMID:16436386 doi:10.1074/jbc.M509785200

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