2x81

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Template:STRUCTURE 2x81

STRUCTURE OF AURORA A IN COMPLEX WITH MLN8054

Template:ABSTRACT PUBMED 20426425

About this Structure

2x81 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Sloane D, Trikic M, Chu ML, Lamers M, Mason C, Mueller I, Savory W, Williams DH, Eyers PA. Drug-resistant Aurora A mutants for cellular target validation of the small molecule kinase inhibitors MLN8054 and MLN8237. ACS Chem Biol. 2010 Apr 28. PMID:20426425 doi:10.1021/cb100053q

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