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3ooz

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Revision as of 06:42, 31 August 2011 by OCA (Talk | contribs)
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Image:3ooz.jpg

Template:STRUCTURE 3ooz

Bace1 in complex with the aminohydantoin Compound 102

Template:ABSTRACT PUBMED 20880704

About this Structure

3ooz is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Malamas MS, Robichaud A, Erdei J, Quagliato D, Solvibile W, Zhou P, Morris K, Turner J, Wagner E, Fan K, Olland A, Jacobsen S, Reinhart P, Riddell D, Pangalos M. Design and synthesis of aminohydantoins as potent and selective human beta-secretase (BACE1) inhibitors with enhanced brain permeability. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6597-605. Epub 2010 Sep 15. PMID:20880704 doi:10.1016/j.bmcl.2010.09.029

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OCA

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