Urokinase

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Template:STRUCTURE 3ig6

Urokinase (UK) is a serine protease whose principal substrate is plasminogen – the inactive zymogen of plasmin. UK consists of 3 domains: ligand-binding domain and kringle and growth factor domains. Prourokinase (PUK) is the inactive zymogen of UK which becomes active by proteolytic cleavage.

Contents

3D Structures of urokinase

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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