Transketolase

From Proteopedia

Transketolase

Transketolase (TKT) catalyzes two opposite reactions. The synthesis of sedoheptulose-7-P in the pentose phosphate pathway using thiamine diphosphate (TPP) as co-factor; and the conversion of sedoheptulose-7-P and glyceraldehyde-3-P to aldose and ketose in the Calvin cycle.

1trk – yTKT – yeast 1ay0 – yTKT (mutant) 2e6k – TKT – Thermus thermophilus 3hyl – BaTKT – Bacillus anthracis 3kom – TKT (mutant) – Francisella tularensis 3l84 – CjTKT – Campylobacter jejuni

Transketolase binary complexes

3m49 – BaTKT + TPP 3mos, 3ooy – TKT + TPP - human 1tka, 1tkb, 1tkc – yTKT + TPP analog 1gpu - yTKT + TPP derivative 1itz - TKT + TPP – maize 1qgd - EcTKT + TPP – Escherichia coli 1r9j - TKT + TPP – Leishmania mexicana

Transketolase ternary complexes

3m7i, 3m6l – CjTKT + TPP + ribose 5-P 3m34 - CjTKT + TPP + Ca 1ngs - yTKT + TPP + Ca + erythrose-4-P 2r5n – EcTKT + TPP + ribose 5-P 2r8o - EcTKT + TPP + xylulose 5-P 2r8p - EcTKT + TPP + fructose 6-P