3s3v

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Image:3s3v.jpg

Template:STRUCTURE 3s3v

human dihydrofolate reductase Q35K/N64F double mutant binary complex with trimethoprim

Template:ABSTRACT PUBMED 21684339

About this Structure

3s3v is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Cody V, Pace J, Piraino J, Queener SF. Crystallographic analysis reveals a novel second binding site for trimethoprim in active site double mutants of human dihydrofolate reductase. J Struct Biol. 2011 Oct;176(1):52-9. Epub 2011 Jun 13. PMID:21684339 doi:10.1016/j.jsb.2011.06.001

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