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3sr4

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Image:3sr4.jpg

Template:STRUCTURE 3sr4

Crystal Structure of Human DOT1L in Complex with a Selective Inhibitor

Template:ABSTRACT PUBMED 21936531

About this Structure

3sr4 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Yao Y, Chen P, Diao J, Cheng G, Deng L, Anglin JL, Prasad BV, Song Y. Selective Inhibitors of Histone Methyltransferase DOT1L: Design, Synthesis and Crystallographic Studies. J Am Chem Soc. 2011 Sep 21. PMID:21936531 doi:10.1021/ja206312b

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