Glycosyltransferase

From Proteopedia

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Template:STRUCTURE 1cxh

Glycosyltransferase (GT) are enzymes which catalyze the transfer of monosaccharide to alcohol, carbohydrate, protein or inorganic phosphate.

3D structures of glycosyltransferase

Cyclodextrin GT (CGT)

1cxi - BcCGT – Bacillus circulans

1tcm, 4cgt, 7cgt, 1kck, 1kcl, 1ot1, 1ot2, 1pez, 1pj9, 1v3j, 1v3k - BcCGT (mutant)

1ciu – TtCGT – Thermoanaerobacterium thermosulfurigenes

3bmv, 3bmw – TtCGT (mutant)

CGT binary complexes

1cxe, 1cxh – BcCGT + substrate

1cxf, 5cgt, 8cgt, 9cgt, 1cxk, 1eo5, 1eo7 - BcCGT (mutant) + substrate

3cgt - BcCGT (mutant) + b-cyclodextrin

1d3c - BcCGT (mutant) + g-cyclodextrin

6cgt - BcCGT (mutant) + HOXA

2dij, 1dtu - BcCGT (mutant) + inhibitor

1cxl - BcCGT (mutant) + reaction intermediate

2cxg, 1ukq – BcCGT + acarbose-derivative

1uks, 1ukt, 1v3l, 1v3m – BcCGT (mutant) + acarbose-derivative

1a47 – TtCGT + inhibitor

Maltose GT

1gju, 1lwh – TmMCG – Thermotoga maritima

1gjw – TmMCG + maltose

1lwj - TmMGT + acarbose

Human GT

1lz0 – hGT A - hGT A catalytic domain + inhibitor

1r7y, 1r81 - hGT A catalytic domain + inhibitor + UDP-derivative

1lz7 – hGT B catalytic domain

1r7u, 1r7x - hGT B catalytic domain + inhibitor

1r80, 1r82 - hGT B catalytic domain + inhibitor + UDP-derivative

1lzi – hGT A catalytic domain + UDP + H antigen acceptor

1lzj – hGT B catalytic domain + UDP + H antigen acceptor

1wt0, 1wsz, 1wt3, 2o1f, 2o1g, 3i0c, 3i0h – hGT ABO(H) (mutant)

1wt1, 1wt2, 2o1h, 3i0d, 3i0i - hGT ABO(H) (mutant) + UDP

3i0e, 3i0j - hGT ABO(H) (mutant) + H-antigen

3i0f, 3i0k - hGT ABO(H) (mutant) + H-antigen + UDP

3i0g, 3i0l - hGT ABO(H) (mutant) + DA + UDP-Gal

Oleandomycin GT

2iya, 2iyf – GT – Strepromyces antibioticus

Flavonoid GT

3hbf – MtGT + UDP + myricetin – Medicago truncatula

3hbj - MtGT + UDP

1nzd – T4b-GT + UDP-glucose – Phage T4

2nzf - T4b-GT (mutant) + UDP-glucose

2iuy, 2iv3 – SvGT – Stretptomyces viridochromogenes

3hzs – GT – Staphylococcus aureus

3mbo – GT + UDP + malate – Bacillus anthracis

3oy7 – GT + GDP-mannose – cholera virus

3pnn – GT – Porphyromonas gingivalis

2q3e, 3q3i – ApGT – Actinobacillus pleuropneumomiae

3q3h – ApGT + UDP-Glc

1iir – AoUDP-GT – Amycolatopsis orientalis

1pn3, 1pnv, 1rrv – AoGT + TDP + vancomycin