Shiga toxin

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spinqualitylabelsall models Shiga Toxin Type 2 (Stx2) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Introduction

Shiga Toxins are a family of AB5 toxins which cause dysentery in humans. They are primarily secreted by Shiga toxin-encoding Escherichia coli (STEC), notably by the 0157:H7 strain. The stx gene is not endogenous to these strains, but introduced by environmental prophages of the lambda bacteriophage family and incorporated into the E. Coli genome1.

Citations

1 Bacteriophage control of Shiga Toxin 1 production and release by Escherichia coli