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3sfx

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Revision as of 07:11, 30 October 2011 by OCA (Talk | contribs)
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Image:3sfx.png

Template:STRUCTURE 3sfx

Cryptococcus neoformans protein farnesyltransferase in complex with FPT-II and tipifarnib

Template:ABSTRACT PUBMED 21816822

About this Structure

3sfx is a 2 chain structure with sequence from Cryptococcus neoformans. Full crystallographic information is available from OCA.

Reference

  • Hast MA, Nichols CB, Armstrong SM, Kelly SM, Hellinga HW, Alspaugh JA, Beese LS. Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens. J Biol Chem. 2011 Oct 7;286(40):35149-62. Epub 2011 Aug 4. PMID:21816822 doi:10.1074/jbc.M111.250506

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