3r0i
From Proteopedia
IspC in complex with an N-methyl-substituted hydroxamic acid
Template:ABSTRACT PUBMED 21866890
About this Structure
3r0i is a 2 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.
Reference
- Behrendt CT, Kunfermann A, Illarionova V, Matheeussen A, Pein MK, Grawert T, Kaiser J, Bacher A, Eisenreich W, Illarionov B, Fischer M, Maes L, Groll M, Kurz T. Reverse Fosmidomycin Derivatives against the Antimalarial Drug Target IspC (Dxr). J Med Chem. 2011 Aug 25. PMID:21866890 doi:10.1021/jm200694q
Categories: 1-deoxy-D-xylulose-5-phosphate reductoisomerase | Escherichia coli k-12 | Bacher, A. | Behrendt, C T. | Eisenreich, W. | Fischer, M. | Graewert, T. | Groll, M. | Illarionov, B. | Illarionova, V. | Kunfermann, A. | Kurz, T. | Maes, L. | Matheeussen, A. | Pein, M K. | Antimalarial agent | Cytosol | Inhibitor | ISPC | Mn | Nadph | Non-mevalonate pathway | Oxidoreductase-antibiotic complex | Reductoisomerase of desoxy-xylulose-5p to methyl-erythritol-3p | Reverse hydroxamic acid ligand binding | Rossmann fold
