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spinqualitylabelsall models PDB ID 2zta Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
2zta, resolution 1.80Å ()
Non-Standard Residues:
Structural annotation: Resources: UniProt : P03069
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml

Contents 1 GCN4 - Leucine Zipper 2 About this Structure 3 See Also 4 Reference

GCN4 - Leucine Zipper

A specific DNA complex of the 65-residue, N-terminal fragment of the yeast transcriptional activator, GAL4, has been analysed at 2.7 A resolution by X-ray crystallography. The protein binds as a dimer to a symmetrical 17-base-pair sequence. A small, recognizes a conserved CCG triplet at each end of the site through direct contacts with the major groove. A short coiled-coil dimerization element imposes 2-fold symmetry. A segment of extended polypeptide chain links the metal-binding module to the dimerization element and specifies the length of the site. The relatively open structure of the complex would allow another protein to bind coordinately with GAL4.

spinqualitylabelsall models PDB ID 1ysa Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
1ysa, resolution 2.90Å ()
Structural annotation: Resources: CATH : 1Ysac00, 1Ysad00 InterPro : Ipr011616, Ipr004827 Pfam : PF00170 SCOP : d1ysac_, d1ysad_ UniProt : P03069
Functional annotation: Cellular component: nucleus Biological process: positive regulation of gene-specific transcription involved in unfolded protein response amino acid biosynthetic process regulation of transcription, DNA-dependent transcription regulation of transcription from RNA polymerase II promoter Molecular function: protein dimerization activity transcription factor activity DNA binding sequence-specific DNA binding
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml

About this Structure

2zta is a 2 chain structure formed by

See Also

• Hydrogen in macromolecular models

Reference

• Marmorstein R, Carey M, Ptashne M, Harrison SC. DNA recognition by GAL4: structure of a protein-DNA complex. Nature. 1992 Apr 2;356(6368):408-14. PMID:1557122 doi:http://dx.doi.org/10.1038/356408a0