3qgn

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Image:3qgn.png

Template:STRUCTURE 3qgn

Contents

The allosteric E*-E equilibrium is a key property of the trypsin fold

Template:ABSTRACT PUBMED 21707111

About this Structure

3qgn is a 2 chain structure of Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Niu W, Chen Z, Gandhi PS, Vogt AD, Pozzi N, Pelc LA, Zapata F, Di Cera E. Crystallographic and Kinetic Evidence of Allostery in a Trypsin-like Protease. Biochemistry. 2011 Jun 30. PMID:21707111 doi:10.1021/bi200878c
  • Niu W, Chen Z, Bush-Pelc LA, Bah A, Gandhi PS, Di Cera E. Mutant N143P reveals how Na+ activates thrombin. J Biol Chem. 2009 Dec 25;284(52):36175-85. Epub 2009 Oct 21. PMID:19846563 doi:10.1074/jbc.M109.069500

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