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2yge

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Revision as of 12:17, 16 November 2011 by OCA (Talk | contribs)

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Image:2yge.jpg

Template:STRUCTURE 2yge

E88G-N92L MUTANT OF N-TERM HSP90 COMPLEXED WITH GELDANAMYCIN

Template:ABSTRACT PUBMED 21778327

About this Structure

2yge is a 1 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

Millson SH, Chua CS, Roe SM, Polier S, Solovieva S, Pearl LH, Sim TS, Prodromou C, Piper PW. Features of the Streptomyces hygroscopicus HtpG reveal how partial geldanamycin resistance can arise with mutation to the ATP binding pocket of a eukaryotic Hsp90. FASEB J. 2011 Nov;25(11):3828-37. Epub 2011 Jul 21. PMID:21778327 doi:10.1096/fj.11-188821