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3mw1

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Revision as of 07:05, 7 December 2011 by OCA (Talk | contribs)
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Image:3mw1.png

Template:STRUCTURE 3mw1

Contents

p38 kinase Crystal structure in complex with small molecule inhibitor

Template:ABSTRACT PUBMED 21999461

About this Structure

3mw1 is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Lumeras W, Vidal L, Vidal B, Balague C, Orellana A, Maldonado M, Dominguez M, Segarra V, Caturla F. 1,7-Naphthyridine 1-Oxides as Novel Potent and Selective Inhibitors of p38 Mitogen Activated Protein Kinase. J Med Chem. 2011 Nov 24;54(22):7899-910. Epub 2011 Oct 31. PMID:21999461 doi:10.1021/jm200975u
  • Lumeras W, Caturla F, Vidal L, Esteve C, Balague C, Orellana A, Dominguez M, Roca R, Huerta JM, Godessart N, Vidal B. Design, Synthesis, and Structure-Activity Relationships of Aminopyridine N-Oxides, a Novel Scaffold for the Potent and Selective Inhibition of p38 Mitogen Activated Protein Kinase. J Med Chem. 2009 Aug 14. PMID:19678708 doi:10.1021/jm9008604

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OCA

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