4a07

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Image:4a07.png

Template:STRUCTURE 4a07

HUMAN PDK1 KINASE DOMAIN IN COMPLEX WITH ALLOSTERIC ACTIVATOR PS171 BOUND TO THE PIF-POCKET

Template:ABSTRACT PUBMED 22118680

About this Structure

4a07 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Lopez-Garcia LA, Schulze JO, Frohner W, Zhang H, Suss E, Weber N, Navratil J, Amon S, Hindie V, Zeuzem S, Jorgensen TJ, Alzari PM, Neimanis S, Engel M, Biondi RM. Allosteric Regulation of Protein Kinase PKCzeta by the N-Terminal C1 Domain and Small Compounds to the PIF-Pocket. Chem Biol. 2011 Nov 23;18(11):1463-1473. PMID:22118680 doi:10.1016/j.chembiol.2011.08.010

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