4a55
From Proteopedia
Crystal structure of p110alpha in complex with iSH2 of p85alpha and the inhibitor PIK-108
Template:ABSTRACT PUBMED 22120714
About this Structure
4a55 is a 2 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.
Reference
- Hon WC, Berndt A, Williams RL. Regulation of lipid binding underlies the activation mechanism of class IA PI3-kinases. Oncogene. 2011 Nov 28. doi: 10.1038/onc.2011.532. PMID:22120714 doi:10.1038/onc.2011.532
Categories: Homo sapiens | Mus musculus | Berndt, A. | Hon, W C. | Williams, R L. | Cancer mutation | Enzyme regulation | Growth factor signalling | Lipid kinase | Membrane binding | Non-atp competitive ligand binding site | Oncogene | Pi3-kinase inhibitor | Structure-activity relationship | Transferase | Tumour
