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3u1y

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Image:3u1y.jpg

Template:STRUCTURE 3u1y

Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections

Template:ABSTRACT PUBMED 22175825

About this Structure

3u1y is a 2 chain structure with sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.

Reference

  • Brown MF, Reilly U, Abramite JA, Arcari JT, Oliver R, Barham RA, Che Y, Chen JM, Collantes EM, Chung SW, Desbonnet C, Doty J, Doroski M, Engtrakul JJ, Harris TM, Huband M, Knafels J, Leach KL, Liu S, Marfat A, Marra A, McElroy E, Melnick M, Menard CA, Montgomery JI, Mulllins L, Noe MC, O'Donnell J, Penzien J, Plummer MS, Price LM, Shanmugasundaram V, Thoma C, Uccello D, Warmus J, Wishka DG. Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections. J Med Chem. 2011 Dec 18. PMID:22175825 doi:10.1021/jm2014748

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