4a92

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Image:4a92.png

Template:STRUCTURE 4a92

Full-length HCV NS3-4A protease-helicase in complex with a macrocyclic protease inhibitor.

Template:ABSTRACT PUBMED 22160684

About this Structure

4a92 is a 2 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.

Reference

  • Schiering N, D'Arcy A, Villard F, Simic O, Kamke M, Monnet G, Hassiepen U, Svergun DI, Pulfer R, Eder J, Raman P, Bodendorf U. A macrocyclic HCV NS3/4A protease inhibitor interacts with protease and helicase residues in the complex with its full-length target. Proc Natl Acad Sci U S A. 2011 Dec 12. PMID:22160684 doi:10.1073/pnas.1110534108

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OCA

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