2yau

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Template:STRUCTURE 2yau

X-ray structure of the Leishmania infantum tryopanothione reductase in complex with auranofin

Template:ABSTRACT PUBMED 21833767

About this Structure

2yau is a 2 chain structure with sequence from Leishmania infantum. Full crystallographic information is available from OCA.

Reference

  • Ilari A, Baiocco P, Messori L, Fiorillo A, Boffi A, Gramiccia M, Di Muccio T, Colotti G. A gold-containing drug against parasitic polyamine metabolism: the X-ray structure of trypanothione reductase from Leishmania infantum in complex with auranofin reveals a dual mechanism of enzyme inhibition. Amino Acids. 2011 Aug 11. PMID:21833767 doi:10.1007/s00726-011-0997-9

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