4a9h

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Image:4a9h.png

Template:STRUCTURE 4a9h

N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 1-(2-methyl-1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-one

Template:ABSTRACT PUBMED 22136404

About this Structure

4a9h is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Chung CW, Dean TW, Woolven JM, Bamborough P. Fragment-based discovery of bromodomain inhibitors part 1: inhibitor binding modes and implications for lead discovery. J Med Chem. 2011 Dec 5. PMID:22136404 doi:10.1021/jm201320w

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