3cy2
From Proteopedia
Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a beta carboline ligand II
Template:ABSTRACT PUBMED 22136433
About this Structure
3cy2 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Huber K, Brault L, Fedorov O, Gasser C, Filippakopoulos P, Bullock AN, Fabbro D, Trappe J, Schwaller J, Knapp S, Bracher F. 7,8-Dichloro-1-oxo-beta-carbolines as a Versatile Scaffold for the Development of Potent and Selective Kinase Inhibitors with Unusual Binding Modes. J Med Chem. 2012 Jan 12;55(1):403-13. Epub 2012 Jan 3. PMID:22136433 doi:10.1021/jm201286z
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Arrowsmith, C H. | Bountra, C. | Bracher, F. | Bullock, A. | Delft, F von. | Edwards, A M. | Fedorov, O. | Filippakopoulos, P. | Huber, K. | Knapp, S. | Pike, A C.W. | SGC, Structural Genomics Consortium. | Alternative initiation | Atp-binding | Host-virus interaction | Kinase | Manganese | Membrane | Metal-binding | Nucleotide-binding | Nucleus | Oncogene | Phosphoprotein | Pim1 | Proto-oncogene | Serine-threonine | Serine/threonine-protein kinase | Sgc | Structural genomics consortium | Transferase | Viral immunoevasion | Virion | Virulence
