4a31
From Proteopedia
CRYSTAL STRUCTURE OF LEISHMANIA MAJOR N-MYRISTOYLTRANSFERASE (NMT) WITH BOUND MYRISTOYL-COA AND A PYRAZOLE SULPHONAMIDE LIGAND
Template:ABSTRACT PUBMED 22148754
About this Structure
4a31 is a 1 chain structure with sequence from Leishmania major. Full crystallographic information is available from OCA.
Reference
- Brand S, Cleghorn LA, McElroy SP, Robinson DA, Smith VC, Hallyburton I, Harrison JR, Norcross NR, Spinks D, Bayliss T, Norval S, Stojanovski L, Torrie LS, Frearson JA, Brenk R, Fairlamb AH, Ferguson MA, Read KD, Wyatt PG, Gilbert IH. Discovery of a novel class of orally active trypanocidal N-myristoyltransferase inhibitors. J Med Chem. 2012 Jan 12;55(1):140-52. Epub 2011 Dec 7. PMID:22148754 doi:10.1021/jm201091t
Categories: Glycylpeptide N-tetradecanoyltransferase | Leishmania major | Brand, S. | Brenk, R. | Cleghorn, L A.T. | Fairlamb, A H. | Ferguson, M A.J. | Frearson, J A. | Gilbert, I H. | Hallyburton, I. | Harrison, J R. | Mcelroy, S P. | Norcross, N R. | Norval, S. | Read, K D. | Robinson, D A. | Smith, V C. | Spinks, D. | Stojanovski, L. | Torrie, L S. | Wyatt, P G. | Acyltransferase | Drug discovery | Leishmaniasis | Transferase
