3uuo
From Proteopedia
The discovery of potent, selectivity, and orally bioavailable pyrozoloquinolines as PDE10 inhibitors for the treatment of Schizophrenia
Template:ABSTRACT PUBMED 22222034
About this Structure
3uuo is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Ho GD, Yang SW, Smotryski J, Bercovici A, Nechuta T, Smith EM, McElroy W, Tan Z, Tulshian D, McKittrick B, Greenlee WJ, Hruza A, Xiao L, Rindgen D, Mullins D, Guzzi M, Zhang X, Bleickardt C, Hodgson R. The discovery of potent, selective, and orally active pyrazoloquinolines as PDE10A inhibitors for the treatment of Schizophrenia. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1019-22. Epub 2011 Dec 9. PMID:22222034 doi:10.1016/j.bmcl.2011.11.127
Categories: Homo sapiens | Bercovici, A. | Bleickardt, C. | Greenlee, W J. | Guzzi, M. | Ho, G D. | Hodgson, R. | Hruza, A. | McElroy, W. | Mckittrick, B. | Mullins, D. | Nechuta, T. | Rindgen, D. | Smith, E M. | Smotryski, J. | Tan, Z. | Tulshian, D. | Xiao, L. | Yang, S. | Zhang, X. | Hydrolase | Hydrolase-hydrolase inhibitor complex | Inhibitor complex | Mg binding | Zn binding
