4dce

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Image:4dce.jpg

Template:STRUCTURE 4dce

Crystal structure of human anaplastic lymphoma kinase in complex with a piperidine-carboxamide inhibitor

Template:ABSTRACT PUBMED 22263917

About this Structure

4dce is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bryan MC, Whittington DA, Doherty EM, Falsey JR, Cheng AC, Emkey R, Brake RL, Lewis RT. Rapid Development of Piperidine Carboxamides as Potent and Selective Anaplastic Lymphoma Kinase Inhibitors. J Med Chem. 2012 Jan 20. PMID:22263917 doi:10.1021/jm201565s

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