3u6i

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Template:STRUCTURE 3u6i

Crystal structure of c-Met in complex with pyrazolone inhibitor 58a

Template:ABSTRACT PUBMED 22320327

About this Structure

3u6i is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Liu L, Norman MH, Lee M, Xi N, Siegmund A, Boezio AA, Booker S, Choquette D, D'Angelo ND, Germain J, Yang K, Yang Y, Zhang Y, Bellon SF, Whittington DA, Harmange JC, Dominguez C, Kim TS, Dussault I. Structure-Based Design of Novel Class II c-Met Inhibitors: 2. SAR and Kinase Selectivity Profiles of the Pyrazolone Series. J Med Chem. 2012 Feb 24. PMID:22320327 doi:http://dx.doi.org/10.1021/jm201331s

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