3u88

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Image:3u88.png

Template:STRUCTURE 3u88

Crystal structure of human menin in complex with MLL1 and LEDGF

Template:ABSTRACT PUBMED 22327296

About this Structure

3u88 is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Huang J, Gurung B, Wan B, Matkar S, Veniaminova NA, Wan K, Merchant JL, Hua X, Lei M. The same pocket in menin binds both MLL and JUND but has opposite effects on transcription. Nature. 2012 Feb 12;482(7386):542-6. doi: 10.1038/nature10806. PMID:22327296 doi:10.1038/nature10806

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