This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3u85
From Proteopedia
Crystal structure of human menin in complex with MLL1
Template:ABSTRACT PUBMED 22327296
About this Structure
3u85 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Huang J, Gurung B, Wan B, Matkar S, Veniaminova NA, Wan K, Merchant JL, Hua X, Lei M. The same pocket in menin binds both MLL and JUND but has opposite effects on transcription. Nature. 2012 Feb 12;482(7386):542-6. doi: 10.1038/nature10806. PMID:22327296 doi:10.1038/nature10806
Categories: Histone-lysine N-methyltransferase | Homo sapiens | Huang, J. | Lei, M. | Wan, B. | Cancer | Epigenetic | Jund | Ledgf | Men1 | Menin | Mll | Tpr | Transcription
