3u4w

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Template:STRUCTURE 3u4w

Src in complex with DNA-templated macrocyclic inhibitor MC4b

Template:ABSTRACT PUBMED 22344177

About this Structure

3u4w is a 1 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA.

Reference

Georghiou G, Kleiner RE, Pulkoski-Gross M, Liu DR, Seeliger MA. Highly specific, bisubstrate-competitive Src inhibitors from DNA-templated macrocycles. Nat Chem Biol. 2012 Feb 19. doi: 10.1038/nchembio.792. PMID:22344177 doi:10.1038/nchembio.792

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Categories: Gallus gallus | Non-specific protein-tyrosine kinase | Georghiou, G. | Kleiner, R E. | Liu, D R. | Pulkoski-Gross, M. | Seeliger, M A. | Protein kinase | Src-like inactive conformation | Transferase-transferase inhibitor complex

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