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2y8c

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Image:2y8c.jpg

Template:STRUCTURE 2y8c

Plasmodium falciparum dUTPase in complex with a trityl ligand

Template:ABSTRACT PUBMED 21411327

About this Structure

2y8c is a 3 chain structure with sequence from Plasmodium falciparum. Full crystallographic information is available from OCA.

Reference

  • Baragana B, McCarthy O, Sanchez P, Bosch-Navarrete C, Kaiser M, Brun R, Whittingham JL, Roberts SM, Zhou XX, Wilson KS, Johansson NG, Gonzalez-Pacanowska D, Gilbert IH. beta-Branched acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase. Bioorg Med Chem. 2011 Apr 1;19(7):2378-91. Epub 2011 Feb 17. PMID:21411327 doi:10.1016/j.bmc.2011.02.012

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OCA

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