This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3vjo
From Proteopedia
Crystal structure of the wild-type EGFR kinase domain in complex with AMPPNP.
Template:ABSTRACT PUBMED 22349823
About this Structure
3vjo is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Yoshikawa S, Kukimoto-Niino M, Parker L, Handa N, Terada T, Fujimoto T, Terazawa Y, Wakiyama M, Sato M, Sano S, Kobayashi T, Tanaka T, Chen L, Liu ZJ, Wang BC, Shirouzu M, Kawa S, Semba K, Yamamoto T, Yokoyama S. Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor. Oncogene. 2012 Feb 20. doi: 10.1038/onc.2012.21. PMID:22349823 doi:10.1038/onc.2012.21
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Kukimoto-Niino, M. | Semba, K. | Shirouzu, M. | Yamamoto, T. | Yokoyama, S. | Yoshikawa, S. | Atp binding | Cell cycle | Disease mutation | Drug resistance | Kinase | Phosphorylation | Receptor | Transferase | Transmembrane | Tyrosine-protein kinase
