2yex
From Proteopedia
Synthesis and evaluation of triazolones as checkpoint kinase 1 inhibitors
Template:ABSTRACT PUBMED 22342147
About this Structure
2yex is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Oza V, Ashwell S, Brassil P, Breed J, Ezhuthachan J, Deng C, Grondine M, Horn C, Liu D, Lyne P, Newcombe N, Pass M, Read J, Su M, Toader D, Yu D, Yu Y, Zabludoff S. Synthesis and evaluation of triazolones as checkpoint kinase 1 inhibitors. Bioorg Med Chem Lett. 2012 Mar 15;22(6):2330-7. Epub 2012 Feb 1. PMID:22342147 doi:10.1016/j.bmcl.2012.01.043
- Oza V, Ashwell S, Brassil P, Breed J, Deng C, Ezhuthachan J, Haye H, Horn C, Janetka J, Lyne P, Newcombe N, Otterbien L, Pass M, Read J, Roswell S, Su M, Toader D, Yu D, Yu Y, Valentine A, Webborn P, White A, Zabludoff S, Zheng X. Discovery of a novel class of triazolones as Checkpoint Kinase inhibitors--hit to lead exploration. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5133-8. Epub 2010 Jul 29. PMID:20673630 doi:10.1016/j.bmcl.2010.07.015
