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3p0v

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Revision as of 06:20, 21 March 2012 by OCA (Talk | contribs)
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Image:3p0v.png

Template:STRUCTURE 3p0v

anti-EGFR/HER3 Fab DL11 alone

Template:ABSTRACT PUBMED 22014573

About this Structure

3p0v is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Schaefer G, Haber L, Crocker LM, Shia S, Shao L, Dowbenko D, Totpal K, Wong A, Lee CV, Stawicki S, Clark R, Fields C, Lewis Phillips GD, Prell RA, Danilenko DM, Franke Y, Stephan JP, Hwang J, Wu Y, Bostrom J, Sliwkowski MX, Fuh G, Eigenbrot C. A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies. Cancer Cell. 2011 Oct 18;20(4):472-86. PMID:22014573 doi:10.1016/j.ccr.2011.09.003

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