This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3ll8
From Proteopedia
Crystal Structure of Calcineurin in Complex with AKAP79 Peptide
Template:ABSTRACT PUBMED 22343722
About this Structure
3ll8 is a 5 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Li H, Pink MD, Murphy JG, Stein A, Dell'acqua ML, Hogan PG. Balanced interactions of calcineurin with AKAP79 regulate Ca(2+)-calcineurin-NFAT signaling. Nat Struct Mol Biol. 2012 Feb 19;19(3):337-45. doi: 10.1038/nsmb.2238. PMID:22343722 doi:10.1038/nsmb.2238
- Kissinger CR, Parge HE, Knighton DR, Lewis CT, Pelletier LA, Tempczyk A, Kalish VJ, Tucker KD, Showalter RE, Moomaw EW, et al.. Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex. Nature. 1995 Dec 7;378(6557):641-4. PMID:8524402 doi:http://dx.doi.org/10.1038/378641a0
- Li H, Zhang L, Rao A, Harrison SC, Hogan PG. Structure of calcineurin in complex with PVIVIT peptide: portrait of a low-affinity signalling interaction. J Mol Biol. 2007 Jun 22;369(5):1296-306. Epub 2007 Apr 19. PMID:17498738 doi:10.1016/j.jmb.2007.04.032
Categories: Homo sapiens | Phosphoprotein phosphatase | Hogan, P G. | Li, H. | Akap79 | Beta-augmentation | Calcineurin | Calmodulin-binding | Hydrolase | Hydrolase-calcium binding protein complex | Iron | Lipoprotein | Membrane | Metal-binding | Myristate | Nucleus | Phosphoprotein | Protein phosphatase | Protein targeting | Protein-peptide docking
