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2ylm

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Image:2ylm.png

Template:STRUCTURE 2ylm

Mechanism of USP7 (HAUSP) activation by its C-terminal ubiquitin-like domain (HUBL) and allosteric regulation by GMP-synthetase.

Template:ABSTRACT PUBMED 21981925

About this Structure

2ylm is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Faesen AC, Dirac AM, Shanmugham A, Ovaa H, Perrakis A, Sixma TK. Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase. Mol Cell. 2011 Oct 7;44(1):147-59. PMID:21981925 doi:10.1016/j.molcel.2011.06.034

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