3aox

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Template:STRUCTURE 3aox

X-ray crystal structure of human anaplastic lymphoma kinase in complex with CH5424802

Template:ABSTRACT PUBMED 21575866

About this Structure

3aox is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Sakamoto H, Tsukaguchi T, Hiroshima S, Kodama T, Kobayashi T, Fukami TA, Oikawa N, Tsukuda T, Ishii N, Aoki Y. CH5424802, a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant. Cancer Cell. 2011 May 17;19(5):679-90. PMID:21575866 doi:10.1016/j.ccr.2011.04.004

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