This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4dum
From Proteopedia
Co-crystal structure of eIF4E with inhibitor
Template:ABSTRACT PUBMED 22458568
About this Structure
4dum is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Chen X, Kopecky D, Mihalic J, Jeffries S, Min X, Heath J, Deignan J, Sujen L, Fu Z, Guimaraes C, Li S, Johnstone S, Xu H, Cardozo M, Shen W, Walker N, Kayser F, Wang Z. Structure-guided design, synthesis and evaluation of guanine-derived inhibitors of the eIF4E mRNA-cap interaction. J Med Chem. 2012 Mar 29. PMID:22458568 doi:10.1021/jm300037x
