3s9y

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Image:3s9y.jpg

Template:STRUCTURE 3s9y

Crystal Structure of P. falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP in space group P21, produced from 5-fluoro-6-azido-UMP

Template:ABSTRACT PUBMED 19260677

About this Structure

3s9y is a 4 chain structure with sequence from Plasmodium falciparum. Full crystallographic information is available from OCA.

Reference

  • Bello AM, Konforte D, Poduch E, Furlonger C, Wei L, Liu Y, Lewis M, Pai EF, Paige CJ, Kotra LP. Structure-activity relationships of orotidine-5'-monophosphate decarboxylase inhibitors as anticancer agents. J Med Chem. 2009 Mar 26;52(6):1648-58. PMID:19260677 doi:10.1021/jm801224t

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