2wv8
From Proteopedia
Complex of human dihydroorotate dehydrogenase with the inhibitor 221290
Template:ABSTRACT PUBMED 20183850
About this Structure
2wv8 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Fritzson I, Svensson B, Al-Karadaghi S, Walse B, Wellmar U, Nilsson UJ, da Graca Thrige D, Jonsson S. Inhibition of human DHODH by 4-hydroxycoumarins, fenamic acids, and N-(alkylcarbonyl)anthranilic acids identified by structure-guided fragment selection. ChemMedChem. 2010 Apr 6;5(4):608-17. PMID:20183850 doi:10.1002/cmdc.200900454
Categories: Dihydroorotate dehydrogenase | Homo sapiens | Al-Karadaghi, S. | Dahlberg, L. | Fritzson, I. | Svensson, B. | Walse, B. | Wellmar, U. | Enzyme inhibition | Flavoprotein | Inflamation | Mitochondrion inner membrane | Oxidoreductase | Pyrimidine biosynthesis | Structure-based drug design | Transit peptide | Transmembrane
