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3v5l

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Image:3v5l.jpg

Template:STRUCTURE 3v5l

Crystal Structure of Interleukin-2 Inducible T-cell Kinase Itk Catalytic Domain with Thienopyrazolylindole Inhibitor 542

Template:ABSTRACT PUBMED 22464456

About this Structure

3v5l is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • McLean LR, Zhang Y, Zaidi N, Bi X, Wang R, Dharanipragada R, Jurcak JG, Gillespy TA, Zhao Z, Musick KY, Choi YM, Barrague M, Peppard J, Smicker M, Duguid M, Parkar A, Fordham J, Kominos D. X-ray crystallographic structure-based design of selective thienopyrazole inhibitors for interleukin-2-inducible tyrosine kinase. Bioorg Med Chem Lett. 2012 May 1;22(9):3296-300. Epub 2012 Mar 11. PMID:22464456 doi:10.1016/j.bmcl.2012.03.016

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OCA

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