Glutathione synthetase

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Template:STRUCTURE 2hgs Glutathione synthetase (GSS) is an ATP-dependent enzyme which catalyzes the condensation of γ-glutamylcysteine and glycine to glutathione. GSS is part of the glutathione biosynthesis pathway.

3D structures of glutathione synthetase

1glv, 2glt, 1gsh – EcGSS – Escherichia coli
1m0t – yGSS – yeast
3ln6 – GSS – Streptococcus agalactiae
3ln7 – GSS – Pasteurella multocida
2wyo - GSS + glutathione – Trypanosoma brucei
1gsa – EcGSS + glutathione + ADP
2hgs - GSS + glutathione + ADP – human
1m0w - yGSS + γ-glutamyl-cysteine + AMP-PNP

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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