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3rnu

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Image:3rnu.png

Template:STRUCTURE 3rnu

Structural Basis of Cytosolic DNA Sensing by Innate Immune Receptors

Template:ABSTRACT PUBMED 22483801

About this Structure

3rnu is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Jin T, Perry A, Jiang J, Smith P, Curry JA, Unterholzner L, Jiang Z, Horvath G, Rathinam VA, Johnstone RW, Hornung V, Latz E, Bowie AG, Fitzgerald KA, Xiao TS. Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor. Immunity. 2012 Apr 20;36(4):561-71. Epub 2012 Apr 5. PMID:22483801 doi:10.1016/j.immuni.2012.02.014

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