Lipase lid morph

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spinqualitylabelsall models Candida rugosa lipase (1trh, 1lpm). Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

For an introduction to the structure and function of lipase, please see the article Lipase. This Lipase lid morph article is a supplement to the main article on Lipase.

Candida rugosa lipase (triacylglycerol hydrolase) has been observed in two conformations, with the "lid" closed (1trh) or open (1lpm)^[1]. When open, substrate can access the catalytic triad, Ser209, Glu341, and His449^[1]