3t03

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Template:STRUCTURE 3t03

Crystal structure of PPAR gamma ligand binding domain in complex with a novel partial agonist GQ-16

Template:ABSTRACT PUBMED 22584573

About this Structure

3t03 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Amato AA, Rajagopalan S, Lin JZ, Carvalho BM, Figueira AC, Lu J, Ayers SD, Mottin M, Silveira RL, Souza PC, Mourao RH, Saad MJ, Togashi M, Simeoni LA, Abdalla DS, Skaff MS, Polikarpov I, Lima MC, Galdino SL, Brennan RG, Baxter JD, Pitta IR, Webb P, Phillips KJ, Neves FA. GQ-16, A novel PPARgamma ligand, promotes insulin sensitization without weight gain. J Biol Chem. 2012 May 14. PMID:22584573 doi:10.1074/jbc.M111.332106

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