3h4v

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Image:3h4v.png

Template:STRUCTURE 3h4v

Selective screening and design to identify inhibitors of leishmania major pteridine reductase 1

Template:ABSTRACT PUBMED 18245389

About this Structure

3h4v is a 8 chain structure with sequence from Leishmania major. This structure supersedes the now removed PDB entry 2p8k. Full crystallographic information is available from OCA.

Reference

  • Cavazzuti A, Paglietti G, Hunter WN, Gamarro F, Piras S, Loriga M, Allecca S, Corona P, McLuskey K, Tulloch L, Gibellini F, Ferrari S, Costi MP. Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development. Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1448-53. Epub 2008 Feb 1. PMID:18245389

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