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2wuz

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Image:2wuz.png

Template:STRUCTURE 2wuz

X-ray structure of CYP51 from Trypanosoma cruzi in complex with fluconazole in alternative conformation

Template:ABSTRACT PUBMED 20386598

About this Structure

2wuz is a 2 chain structure with sequence from Trypanosoma cruzi. Full crystallographic information is available from OCA.

Reference

  • Chen CK, Leung SS, Guilbert C, Jacobson MP, McKerrow JH, Podust LM. Structural characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei bound to the antifungal drugs posaconazole and fluconazole. PLoS Negl Trop Dis. 2010 Apr 6;4(4):e651. PMID:20386598 doi:10.1371/journal.pntd.0000651

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