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2f67

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Image:2f67.png

Template:STRUCTURE 2f67

Crystal structure of Nucleoside 2-deoxyribosyltransferase from Trypanosoma brucei at 1.6 A resolution with BENZO[CD]INDOL-2(1H)-ONE bound

Template:ABSTRACT PUBMED 17004709

About this Structure

2f67 is a 2 chain structure with sequence from Trypanosoma brucei. Full crystallographic information is available from OCA.

Reference

  • Bosch J, Robien MA, Mehlin C, Boni E, Riechers A, Buckner FS, Van Voorhis WC, Myler PJ, Worthey EA, DeTitta G, Luft JR, Lauricella A, Gulde S, Anderson LA, Kalyuzhniy O, Neely HM, Ross J, Earnest TN, Soltis M, Schoenfeld L, Zucker F, Merritt EA, Fan E, Verlinde CL, Hol WG. Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase. J Med Chem. 2006 Oct 5;49(20):5939-46. PMID:17004709 doi:http://dx.doi.org/10.1021/jm060429m

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