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2a75
From Proteopedia
Trypanosoma rangeli Sialidase In Complex With 2,3- Difluorosialic Acid (Covalent Intermediate)
Template:ABSTRACT PUBMED 16298994
About this Structure
2a75 is a 1 chain structure with sequence from Trypanosoma rangeli. Full crystallographic information is available from OCA.
Reference
- Watts AG, Oppezzo P, Withers SG, Alzari PM, Buschiazzo A. Structural and kinetic analysis of two covalent sialosyl-enzyme intermediates on Trypanosoma rangeli sialidase. J Biol Chem. 2006 Feb 17;281(7):4149-55. Epub 2005 Nov 18. PMID:16298994 doi:http://dx.doi.org/10.1074/jbc.M510677200
- Lin TW, Melgar MM, Kurth D, Swamidass SJ, Purdon J, Tseng T, Gago G, Baldi P, Gramajo H, Tsai SC. Structure-based inhibitor design of AccD5, an essential acyl-CoA carboxylase carboxyltransferase domain of Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3072-7. Epub 2006 Feb 21. PMID:16492739
- Demir O, Roitberg AE. Modulation of catalytic function by differential plasticity of the active site: case study of Trypanosoma cruzi trans-sialidase and Trypanosoma rangeli sialidase. Biochemistry. 2009 Apr 21;48(15):3398-406. PMID:19216574 doi:10.1021/bi802230y
