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2qu5

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Image:2qu5.png

Template:STRUCTURE 2qu5

Contents

Crystal structure of the VEGFR2 kinase domain in complex with a benzimidazole inhibitor

Template:ABSTRACT PUBMED 17696416

About this Structure

2qu5 is a 1 chain structure of Vascular Endothelial Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Potashman MH, Bready J, Coxon A, DeMelfi TM Jr, DiPietro L, Doerr N, Elbaum D, Estrada J, Gallant P, Germain J, Gu Y, Harmange JC, Kaufman SA, Kendall R, Kim JL, Kumar GN, Long AM, Neervannan S, Patel VF, Polverino A, Rose P, Plas S, Whittington D, Zanon R, Zhao H. Design, synthesis, and evaluation of orally active benzimidazoles and benzoxazoles as vascular endothelial growth factor-2 receptor tyrosine kinase inhibitors. J Med Chem. 2007 Sep 6;50(18):4351-73. Epub 2007 Aug 15. PMID:17696416 doi:10.1021/jm070034i

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